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HomeDosingDosingRecommended dosingCYP3A4 coadministrationDosage modifications for adverse reactionsEfficacyAdjuvant treatment
of RCC
Primary Endpoint
Advanced RCCPrimary EndpointSecondary EndpointsAdvanced pNETPrimary EndpointSecondary EndpointsImatinib-resistant or
-intolerant GIST
Primary EndpointSecondary Endpoints
Safety ProfileAdjuvant treatment
of RCC
Important Safety InformationAdverse reactionsLab abnormalitiesDiscontinuation rates
Advanced RCCImportant Safety InformationAdverse reactionsLab abnormalitiesDiscontinuation ratesAdvanced pNETImportant Safety InformationAdverse reactionsLab abnormalitiesDiscontinuation ratesImatinib-resistant or
-intolerant GIST
Important Safety InformationAdverse reactionsLab abnormalitiesDiscontinuation rates
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INDICATIONS

SUTENT® (sunitinib malate) is indicated for:

  • the treatment of adult patients with gastrointestinal stromal tumor (GIST) after disease progression on or intolerance to imatinib mesylate
  • the treatment of adult patients with advanced renal cell carcinoma (RCC)
  • the adjuvant treatment of adult patients at high risk of recurrent RCC following nephrectomy
  • the treatment of progressive, well-differentiated pancreatic neuroendocrine tumors (pNET) in adult patients with unresectable locally advanced or metastatic disease